17 June 2022 · PPIs may enhance warfarin anticoagulation. Patients on warfarin require counselling when starting on a PPI and INR monitored appropriately.
22 May 2023 · Avoid the combined use of clopidogrel with omeprazole or esomeprazole due to a significant interaction. Other PPIs are considered safe with clopidogrel.
4 April 2023 · Although no interaction between bisphosphonates and PPIs is documented, the increased risk of fractures when given together should be reviewed and managed
5 March 2024 · Antacids, alginates, H2-receptor antagonists or proton pump inhibitors can be used during breastfeeding. Recommendations are for full term and healthy infants.