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Find PERT alternatives and equivalences

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Find constituents and alternatives for PERTs. We give the enzyme constituents by product and by quantity for each product, as well as alternatives.

About the tool

Purpose

This tool provides options for PERTs by matching a patient’s current therapy against equivalent UK licensed products. It also states the enzymatic constituents by product and individual dose.

Included recommendations

The tool includes recommendations for both children and adults.

Recommendations for children have been developed in close consultation with colleagues from the Neonatal and Paediatric Pharmacy Group; recommendations for adults are as published in the Pancreatic Society of Great Britain and Ireland position statement on the PERT shortage.

Use the tool

Select the options for your patient and their current therapy to see suggested alternatives.

Adult or child

Creon Micro Pancreatin 60.12 mg Gastro-resistant Granules

Constituents

Each 100mg scoop contains:

  • Amylase 3600 units
  • Lipase 5000 units
  • Protease 200 units

5 scoops of Creon Micro contain:

  • Amylase 18,000 units
  • Lipase 25,000 units
  • Protease 1000 units

Equivalent products to 5 scoops

5 scoops of Creon Micro could be replaced with:

  • 1 × Nutrizym 22 capsule
  • 3 × Creon 10,000 capsules
  • 1 × Creon 25,000 capsules
  • 8 × Pancrex V 125mg capsules
  • 3 × Pancrex V 340mg capsules
  • Half a 2.5ml spoonful of Pancrex V powder

10 scoops of Creon Micro contain:

  • Amylase 36,000 units
  • Lipase 50,000 units
  • Protease 2000 units

Equivalent products to 10 scoops

10 scoops of Creon Micro could be replaced with:

  • 5 × Creon 10,000 capsules
  • 2 × Creon 25,000 capsules
  • 2 × Nutrizym 22 capsules
  • 16 × Pancrex V 125mg capsules
  • 6 × Pancrex V 340mg capsules
  • 1 × 2.5ml spoonful Pancrex V powder

15 scoops of Creon Micro contain:

  • Amylase 54,000 units
  • Lipase 75,000 units
  • Protease 3000 units

Equivalent products to 15 scoops

15 scoops of Creon Micro could be replaced with:

  • 8 × Creon 10,000 capsules
  • 3 × Creon 25,000 capsules
  • 3 × Nutrizym 22 capsules
  • 24 × Pancrex V 125mg capsules
  • 9 × Pancrex V 340mg capsules
  • One and a half 2.5ml spoonfuls of Pancrex V powder

20 scoops of Creon Micro contain:

  • Amylase 72,000 units
  • Lipase 100,000 units
  • Protease 4000 units

Equivalent products to 20 scoops

20 scoops of Creon Micro could be replaced with:

  • 10 × Creon 10,000 capsules
  • 4 × Creon 25,000 capsules
  • 4 × Nutrizym 22 capsules
  • 32 × Pancrex V 125mg capsules
  • 12 × Pancrex V 340mg capsules
  • 2 × 2.5ml spoonfuls of Pancrex V powder

25 scoops of Creon Micro contain:

  • Amylase 90,000 units
  • Lipase 125,000 units
  • Protease 5000 units

Equivalent products to 25 scoops

25 scoops of Creon Micro could be replaced with:

  • 13 × Creon 10,000 capsules
  • 5 × Creon 25,000 capsules
  • 5 × Nutrizym 22 capsules
  • 40 × Pancrex V 125mg capsules
  • 15 × Pancrex V 340mg capsules
  • Two and a half 2.5ml spoonfuls of Pancrex V powder

30 scoops of Creon Micro contain:

  • Amylase 108,000 units
  • Lipase 150,000 units
  • Protease 6000 units

Equivalent products to 30 scoops

30 scoops of Creon Micro could be replaced with:

  • 15 × Creon 10,000 capsules
  • 6 × Creon 25,000 capsules
  • 6 × Nutrizym 22 capsules
  • 48 × Pancrex V 125mg capsules
  • 18 × Pancrex V 340mg capsules
  • 3 × 2.5ml spoonfuls of Pancrex V powder

2 scoops of Creon Micro contain:

  • Amylase 7200 units
  • Lipase 10,000 units
  • Protease 400 units

Equivalent products to 2 scoops

2 scoops of Creon Micro could be replaced with:

  • 1 × Creon 10,000 capsules
  • Half a Creon 25,000 capsule
  • 2 × Pancrex V 340mg capsules
  • Quarter a spoon of a 2.5ml spoonful of Pancrex V powder

4 scoops of Creon Micro contain:

  • Amylase 14,400 units
  • Lipase 20,000 units
  • Protease 800 units

Equivalent products to 4 scoops

4 scoops of Creon Micro could be replaced with:

  • 2 × Creon 10,000 capsules
  • 1 × Creon 25,000 capsules
  • 3 × Pancrex V 340mg capsules
  • Half of a 2.5ml spoonful of Pancrex V powder

6 scoops of Creon Micro contain:

  • Amylase 21,600 units
  • Lipase 30,000 units
  • Protease 1200 units

Equivalent products to 6 scoops

6 scoops of Creon Micro could be replaced with:

  • 3 × Creon 10,000 capsules
  • One and a half Creon 25,000 capsules
  • 5 × Pancrex V 340mg capsules
  • Three-quarters of a spoonful of a 2.5ml spoonful of Pancrex V powder

8 scoops of Creon Micro contain:

  • Amylase 28,800 units
  • Lipase 40,000 units
  • Protease 1600 units

Equivalent products to 8 scoops

8 scoops of Creon Micro could be replaced with:

  • 4 × Creon 10,000 capsules
  • 2 × Creon 25,000 capsules
  • 6 × Pancrex V 340mg capsules
  • 1 × 2.5ml spoonful of Pancrex V powder

10 scoops of Creon Micro contain:

  • Amylase 36,000 units
  • Lipase 50,000 units
  • Protease 2000 units

Equivalent products to 10 scoops

10 scoops of Creon Micro could be replaced with:

  • 5 × Creon 10,000 capsules
  • 2 × Creon 25,000 capsules
  • 6 × Pancrex V 340mg capsules
  • 1 × 2.5ml spoonful of Pancrex V powder

12 scoops of Creon Micro contain:

  • Amylase 43,200 units
  • Lipase 60,000 units
  • Protease 2400 units

Equivalent products to 12 scoops

12 scoops of Creon Micro could be replaced with:

  • 6 × Creon 10,000 capsules
  • Two and a half Creon 25,000 capsules
  • 8 × Pancrex V 340mg capsules
  • One and a quarter spoonfuls of a 2.5ml spoonful of Pancrex V powder

14 scoops of Creon Micro contain:

  • Amylase 50,400 units
  • Lipase 70,000 units
  • Protease 2800 units

Equivalent products to 14 scoops

14 scoops of Creon Micro could be replaced with:

  • 7 × Creon 10,000 capsules
  • 3 × Creon 25,000 capsules
  • 9 × Pancrex V 340mg capsules
  • One and a half spoonfuls of a 2.5ml spoonful of Pancrex V powder

16 scoops of Creon Micro contain:

  • Amylase 57,600 units
  • Lipase 80,000 units
  • Protease 3200 units

Equivalent products to 16 scoops

16 scoops of Creon Micro could be replaced with:

  • 8 × Creon 10,000 capsules
  • Three and a half Creon 25,000 capsules
  • 11 × Pancrex V 340mg capsules
  • One and three quarter spoons of a 2.5ml spoonful of Pancrex V powder

18 scoops of Creon Micro contain:

  • Amylase 64,800 units
  • Lipase 90,000 units
  • Protease 3600 units

Equivalent products to 18 scoops

18 scoops of Creon Micro could be replaced with:

  • 9 × Creon 10,000 capsules
  • 4 × Creon 25,000 capsules
  • 12 × Pancrex V 340mg capsules
  • 2 × 2.5ml spoonfuls of Pancrex V powder

20 scoops of Creon Micro contain:

  • Amylase 72,000 units
  • Lipase 100,000 units
  • Protease 4000 units

Equivalent products to 20 scoops

20 scoops of Creon Micro could be replaced with:

  • 10 × Creon 10,000 capsules
  • 4 × Creon 25,000 capsules
  • 12 × Pancrex V 340mg capsules
  • 2 × 2.5ml spoonfuls of Pancrex V powder

Creon 10,000 unit capsules

Constituents

Each capsule contains:

  • Amylase 8,000 units
  • Lipase 10,000 units
  • Protease 600 units

3 × Creon 10,000 capsules contain:

  • Amylase 24,000 units
  • Lipase 30,000 units
  • Protease 1800 units

Equivalent products to 3 capsules

3 × Creon 10,000 unit capsules could be replaced with:

  • 5 × scoops of Creon Micro granules
  • 1 × Creon 25,000 capsule
  • 1 × Nutrizym 22 capsule
  • 8 × Pancrex V 125mg capsules
  • 3 × Pancrex V 340mg capsules
  • Half a spoonful of a 2.5ml spoonful of Pancrex V powder

5 × Creon 10,000 capsules contain:

  • Amylase 40,000 units
  • Lipase 50,000 units
  • Protease 3000 units

Equivalent products to 5 capsules

5 × Creon 10,000 unit capsules could be replaced with:

  • 10 × scoops of Creon Micro granules
  • 2 × Creon 25,000 capsules
  • 2 × Nutrizym 22 capsules
  • 16 × Pancrex V 125mg capsules
  • 6 × Pancrex V 340mg capsules
  • 1 × 2.5ml spoonful of Pancrex V powder

8 × Creon 10,000 capsules contain:

  • Amylase 64,000 units
  • Lipase 80,000 units
  • Protease 4800 units

Equivalent products to 8 capsules

8 × Creon 10,000 unit capsules could be replaced with:

  • 15 × scoops of Creon Micro granules
  • 3 × Creon 25,000 capsules
  • 3 × Nutrizym 22 capsules
  • 24 × Pancrex V 125mg capsules
  • 9 × Pancrex V 340mg capsules
  • One and half spoons of a 2.5ml spoonful of Pancrex V powder

10 × Creon 10,000 capsules contain:

  • Amylase 80,000 units
  • Lipase 100,000 units
  • Protease 6000 units

Equivalent products to 10 capsules

10 × Creon 10,000 unit capsules could be replaced with:

  • 20 × scoops of Creon Micro granules
  • 4 × Creon 25,000 capsules
  • 4 × Nutrizym 22 capsules
  • 32 × Pancrex V 125mg capsules
  • 12 × Pancrex V 340mg capsules
  • 2 × 2.5ml spoonful of Pancrex V powder

13 × Creon 10,000 capsules contain:

  • Amylase 104,000 units
  • Lipase 130,000 units
  • Protease 7800 units

Equivalent products to 13 capsules

13 × Creon 10,000 unit capsules could be replaced with:

  • 25 × scoops of Creon Micro granules
  • 5 × Creon 25,000 capsules
  • 5 × Nutrizym 22 capsules
  • 40 × Pancrex V 125mg capsules
  • 15 × Pancrex V 340mg capsules
  • Two and half spoons of a 2.5ml spoonful of Pancrex V powder

15 × Creon 10,000 capsules contain:

  • Amylase 120,000 units
  • Lipase 150,000 units
  • Protease 9000 units

Equivalent products to 15 capsules

15 × Creon 10,000 unit capsules could be replaced with:

  • 30 × scoops of Creon Micro granules
  • 6 × Creon 25,000 capsules
  • 6 × Nutrizym 22 capsules
  • 48 × Pancrex V 125mg capsules
  • 18 × Pancrex V 340mg capsules
  • 3 × 2.5ml spoonful of Pancrex V powder

1 × Creon 10,000 capsule contains:

  • Amylase 8000 units
  • Lipase 10,000 units
  • Protease 600 units

Equivalent products to 1 capsules

1 × Creon 10,000 unit capsule could be replaced with:

  • 2 × scoops of Creon Micro granules
  • Half a Creon 25,000 capsule
  • 2 × Pancrex V 340mg capsules
  • Quarter of a spoon of a 2.5ml spoonful of Pancrex V powder

2 × Creon 10,000 capsules contain:

  • Amylase 16,000 units
  • Lipase 20,000 units
  • Protease 1200 units

Equivalent products to 2 capsules

2 × Creon 10,000 unit capsules could be replaced with:

  • 4 × scoops of Creon Micro granules
  • 1 × Creon 25,000 capsule
  • 3 × Pancrex V 340mg capsules
  • Half of a spoon of a 2.5ml spoonful of Pancrex V powder

3 × Creon 10,000 capsules contain:

  • Amylase 24,000 units
  • Lipase 30,000 units
  • Protease 1800 units

Equivalent products to 3 capsules

3 × Creon 10,000 unit capsules could be replaced with:

  • 6 × scoops of Creon Micro granules
  • One and a half Creon 25,000 capsules
  • 5 × Pancrex V 340mg capsules
  • Three quarters of a spoon of a 2.5ml spoonful of Pancrex V powder

4 × Creon 10,000 capsules contain:

  • Amylase 32,000 units
  • Lipase 40,000 units
  • Protease 2400 units

Equivalent products to 4 capsules

4 × Creon 10,000 unit capsules could be replaced with:

  • 8 × scoops of Creon Micro granules
  • 2 × Creon 25,000 capsules
  • 6 × Pancrex V 340mg capsules
  • 1 × 2.5ml spoonful of Pancrex V powder

5 × Creon 10,000 capsules contain:

  • Amylase 40,000 units
  • Lipase 50,000 units
  • Protease 3000 units

Equivalent products to 5 capsules

5 × Creon 10,000 unit capsules could be replaced with:

  • 10 × scoops of Creon Micro granules
  • 2 × Creon 25,000 capsules
  • 6 × Pancrex V 340mg capsules
  • 1 × 2.5ml spoonful of Pancrex V powder

6 × Creon 10,000 capsules contain:

  • Amylase 48,000 units
  • Lipase 60,000 units
  • Protease 3600 units

Equivalent products to 6 capsules

6 × Creon 10,000 unit capsules could be replaced with:

  • 12 × scoops of Creon Micro granules
  • Two and a half Creon 25,000 capsules
  • 8 × Pancrex V 340mg capsules
  • One and a quarter spoons of a 2.5ml spoonful of Pancrex V powder

7 × Creon 10,000 capsules contain:

  • Amylase 56,000 units
  • Lipase 70,000 units
  • Protease 4200 units

Equivalent products to 7 capsules

7 × Creon 10,000 unit capsules could be replaced with:

  • 14 × scoops of Creon Micro granules
  • 3 × Creon 25,000 capsules
  • 9 × Pancrex V 340mg capsules
  • One and a half spoons of a 2.5ml spoonful of Pancrex V powder

8 × Creon 10,000 capsules contain:

  • Amylase 64,000 units
  • Lipase 80,000 units
  • Protease 4800 units

Equivalent products to 8 capsules

8 × Creon 10,000 unit capsules could be replaced with:

  • 16 × scoops of Creon Micro granules
  • Three and a half Creon 25,000 capsules
  • 11 × Pancrex V 340mg capsules
  • One and three-quarter spoons of a 2.5ml spoonful of Pancrex V powder

9 × Creon 10,000 capsules contain:

  • Amylase 72,000 units
  • Lipase 90,000 units
  • Protease 5400 units

Equivalent products to 9 capsules

9 × Creon 10,000 unit capsules could be replaced with:

  • 18 × scoops of Creon Micro granules
  • 4 × Creon 25,000 capsules
  • 12 × Pancrex V 340mg capsules
  • 2 × 2.5ml spoonful of Pancrex V powder

10 × Creon 10,000 capsules contain:

  • Amylase 80,000 units
  • Lipase 100,000 units
  • Protease 6000 units

Equivalent products to 10 capsules

10 × Creon 10,000 unit capsules could be replaced with:

  • 20 × scoops of Creon Micro granules
  • 4 × Creon 25,000 capsules
  • 12 × Pancrex V 340mg capsules
  • 2 × 2.5ml spoonful of Pancrex V powder

Creon 25,000 unit capsules

Constituents

Each capsule contains:

  • Amylase 18,000 units
  • Lipase 25,000 units
  • Protease 1000 units

1 × Creon 25,000 capsule contains:

  • Amylase 18,000 units
  • Lipase 25,000 units
  • Protease 1000 units

Equivalent products to 1 capsule

1 × Creon 25,000 unit capsule could be replaced with:

  • 5 × scoops of Creon Micro granules
  • 3 × Creon 10,000 capsules
  • 1 × Nutrizym 22 capsule
  • 8 × Pancrex V 125mg capsules
  • 3 × Pancrex V 340mg capsules
  • Half a spoon of a 2.5ml spoonful of Pancrex V powder

2 × Creon 25,000 capsules contain:

  • Amylase 36,000 units
  • Lipase 50,000 units
  • Protease 2000 units

Equivalent products to 2 capsules

2 × Creon 25,000 unit capsules could be replaced with:

  • 10 × scoops of Creon Micro granules
  • 5 × Creon 10,000 capsules
  • 2 × Nutrizym 22 capsules
  • 16 × Pancrex V 125mg capsules
  • 6 × Pancrex V 340mg capsules
  • 1 × 2.5ml spoonful of Pancrex V powder

3 × Creon 25,000 capsules contain:

  • Amylase 54,000 units
  • Lipase 75,000 units
  • Protease 3000 units

Equivalent products to 3 capsules

3 × Creon 25,000 unit capsules could be replaced with:

  • 15 × scoops of Creon Micro granules
  • 8 × Creon 10,000 capsules
  • 3 × Nutrizym 22 capsules
  • 24 × Pancrex V 125mg capsules
  • 9 × Pancrex V 340mg capsules
  • One and half spoons of a 2.5ml spoonful of Pancrex V powder

4 × Creon 25,000 capsules contain:

  • Amylase 72,000 units
  • Lipase 100,000 units
  • Protease 4000 units

Equivalent products to 4 capsules

4 × Creon 25,000 unit capsules could be replaced with:

  • 20 × scoops of Creon Micro granules
  • 10 × Creon 10,000 capsules
  • 4 × Nutrizym 22 capsules
  • 32 × Pancrex V 125mg capsules
  • 12 × Pancrex V 340mg capsules
  • 2 × 2.5ml spoonful of Pancrex V powder

5 × Creon 25,000 capsules contain:

  • Amylase 90,000 units
  • Lipase 125,000 units
  • Protease 5000 units

Equivalent products to 5 capsules

5 × Creon 25,000 unit capsules could be replaced with:

  • 25 × scoops of Creon Micro granules
  • 13 × Creon 10,000 capsules
  • 5 × Nutrizym 22 capsules
  • 40 × Pancrex V 125mg capsules
  • 15 × Pancrex V 340mg capsules
  • Two and a half spoons of a 2.5ml spoonful of Pancrex V powder

6 × Creon 25,000 capsules contain:

  • Amylase 108,000 units
  • Lipase 150,000 units
  • Protease 6000 units

Equivalent products to 6 capsules

6 × Creon 25,000 unit capsules could be replaced with:

  • 30 × scoops of Creon Micro granules
  • 15 × Creon 10,000 capsules
  • 6 × Nutrizym 22 capsules
  • 48 × Pancrex V 125mg capsules
  • 18 × Pancrex V 340mg capsules
  • 3 × 2.5ml spoonful of Pancrex V powder

Half a Creon 25,000 capsule contains:

  • Amylase 9000 units
  • Lipase 12,500 units
  • Protease 500 units

Equivalent products to half a capsule

Half a Creon 25,000 unit capsule could be replaced with:

  • 2 × scoops of Creon Micro granules
  • 1 × Creon 10,000 capsule
  • 2 × Pancrex V 340mg capsules
  • Quarter of a spoon of a 2.5ml spoonful of Pancrex V powder

1 × 25,000 capsule contains:

  • Amylase 18,000 units
  • Lipase 25,000 units
  • Protease 1000 units

Equivalent products to 1 capsule

1 × Creon 25,000 unit capsule could be replaced with:

  • 4 × scoops of Creon Micro granules
  • 2 × Creon 10,000 capsules
  • 3 × Pancrex V 340mg capsules
  • Half of a spoon of a 2.5ml spoonful of Pancrex V powder

One and half a Creon 25,000 capsules contain:

  • Amylase 27,000 units
  • Lipase 37,500 units
  • Protease 1500 units

Equivalent products to one and half a capsules

One and a half a Creon 25,000 unit capsules could be replaced with:

  • 6 × scoops of Creon Micro granules
  • 3 × Creon 10,000 capsules
  • 5 × Pancrex V 340mg capsules
  • Three-quarters of a spoon of a 2.5ml spoonful of Pancrex V powder

2 × 25,000 capsules contain:

  • Amylase 36,000 units
  • Lipase 50,000 units
  • Protease 2000 units

Equivalent products to 2 capsules

2 × Creon 25,000 unit capsules could be replaced with:

  • 8 – 10 × scoops of Creon Micro granules
  • 4 – 5 × Creon 10,000 capsules
  • 6 × Pancrex V 340mg capsules
  • 1 × 2.5ml spoonful of Pancrex V powder

Two and half a Creon 25,000 capsules contain:

  • Amylase 45,000 units
  • Lipase 62,500 units
  • Protease 2500 units

Equivalent products to two and a half a capsules

Two and half a Creon 25,000 unit capsules could be replaced with:

  • 12 × scoops of Creon Micro granules
  • 6 × Creon 10,000 capsules
  • 8 × Pancrex V 340mg capsules
  • One a quarter spoons of a 2.5ml spoonful of Pancrex V powder

3 × 25,000 capsules contain:

  • Amylase 54,000 units
  • Lipase 75,000 units
  • Protease 3000 units

Equivalent products to 3 capsules

3 × Creon 25,000 unit capsules could be replaced with:

  • 14 × scoops of Creon Micro granules
  • 7 × Creon 10,000 capsules
  • 9 × Pancrex V 340mg capsules
  • One and half spoons of a 2.5ml spoonful of Pancrex V powder

Three and half a Creon 25,000 capsules contain:

  • Amylase 63,000 units
  • Lipase 87,500 units
  • Protease 3500 units

Equivalent products to three and a half capsules

Three and a half a Creon 25,000 unit capsules could be replaced with:

  • 16 × scoops of Creon Micro granules
  • 8 × Creon 10,000 capsules
  • 11 × Pancrex V 340mg capsules
  • One and three-quarters of a spoon of a 2.5ml spoonful of Pancrex V powder

4 × 25,000 capsules contain:

  • Amylase 72,000 units
  • Lipase 100,000 units
  • Protease 4000 units

Equivalent products to 4 capsules

4 × Creon 25,000 unit capsules could be replaced with:

  • 18 – 20 × scoops of Creon Micro granules
  • 9 – 10 × Creon 10,000 capsules
  • 12 × Pancrex V 340mg capsules
  • 2 × 2.5ml spoonfuls of Pancrex V powder

Nutrizym 22 capsules

Constituents

Each capsule contains:

  • Amylase 19,800 units
  • Lipase 22,000 units
  • Protease 1100 units

1 × Nutrizym 22 capsule contains:

  • Amylase 19,800 units
  • Lipase 22,000 units
  • Protease 1100 units

Equivalent products to 1 capsule

1 × Nutrizym 22 capsule could be replaced with:

  • 5 × scoops of Creon Micro granules
  • 3 × Creon 10,000 unit capsules
  • 1 × Creon 25,000 unit capsule
  • 8 × Pancrex V 125mg capsules
  • 3 × Pancrex V 340mg capsules
  • Half a spoon of a 2.5ml spoonful of Pancrex V powder

2 × Nutrizym 22 capsules contain:

  • Amylase 39,600 units
  • Lipase 44,000 units
  • Protease 2200 units

Equivalent products to 2 capsules

2 × Nutrizym 22 capsules could be replaced with:

  • 10 × scoops of Creon Micro granules
  • 5 × Creon 10,000 unit capsules
  • 2 × Creon 25,000 unit capsules
  • 16 × Pancrex V 125mg capsules
  • 6 × Pancrex V 340mg capsules
  • 1 × 2.5ml spoonful of Pancrex V powder

3 × Nutrizym 22 capsule contain:

  • Amylase 59,400 units
  • Lipase 66,000 units
  • Protease 3300 units

Equivalent products to 3 capsules

3 × Nutrizym 22 capsules could be replaced with:

  • 15 × scoops of Creon Micro granules
  • 8 × Creon 10,000 unit capsules
  • 3 × Creon 25,000 unit capsules
  • 24 × Pancrex V 125mg capsules
  • 9 × Pancrex V 340mg capsules
  • One and a half spoons of a 2.5ml spoonful of Pancrex V powder

4 × Nutrizym 22 capsules contain:

  • Amylase 79,200 units
  • Lipase 88,000 units
  • Protease 4400 units

Equivalent products to 4 capsules

4 × Nutrizym 22 capsules could be replaced with:

  • 20 × scoops of Creon Micro granules
  • 10 × Creon 10,000 unit capsules
  • 4 × Creon 25,000 unit capsules
  • 32 × Pancrex V 125mg capsules
  • 12 × Pancrex V 340mg capsules
  • 2 × 2.5ml spoonful of Pancrex V powder

5 × Nutrizym 22 capsule contain:

  • Amylase 99,000 units
  • Lipase 110,000 units
  • Protease 5500 units

Equivalent products to 5 capsules

5 × Nutrizym 22 capsules could be replaced with:

  • 25 × scoops of Creon Micro granules
  • 13 × Creon 10,000 unit capsules
  • 5 × Creon 25,000 unit capsules
  • 40 × Pancrex V 125mg capsules
  • 15 × Pancrex V 340mg capsules
  • Two and a half spoons of a 2.5ml spoonful of Pancrex V powder

6 × Nutrizym 22 capsules contain:

  • Amylase 118,800 units
  • Lipase 132,000 units
  • Protease 6600 units

Equivalent products to 6 capsules

6 × Nutrizym 22 capsules could be replaced with:

  • 30 × scoops of Creon Micro granules
  • 15 × Creon 10,000 unit capsules
  • 6 × Creon 25,000 unit capsules
  • 48 × Pancrex V 125mg capsules
  • 18 × Pancrex V 340mg capsules
  • 3 × 2.5ml spoonful of Pancrex V powder

Pancrex V 125mg hard capsules

Constituents

Each capsule contains:

  • Amylase 3300 units
  • Lipase 2950 units
  • Protease 160 units

8 × Pancrex V 125mg hard capsules contain:

  • Amylase 26,400 units
  • Lipase 23,600 units
  • Protease 1280 units

Equivalent products to 8 capsules

8 × Pancrex V 125mg hard capsules could be replaced with:

  • 5 × scoops of Creon Micro granules
  • 3 × Creon 10,000 unit capsules
  • 1 × Creon 25,000 unit capsule
  • 1 × Nutrizym 22 capsule
  • 3 × Pancrex V 340mg capsules
  • Half a spoon of a 2.5ml spoonful of Pancrex V powder

16 × Pancrex V 125mg hard capsules contain:

  • Amylase 52,800 units
  • Lipase 47,200 units
  • Protease 2560 units

Equivalent products to 16 capsules

16 × Pancrex V 125mg hard capsules could be replaced with:

  • 10 × scoops of Creon Micro granules
  • 5 × Creon 10,000 unit capsules
  • 2 × Creon 25,000 unit capsules
  • 2 × Nutrizym 22 capsules
  • 6 × Pancrex V 340mg capsules
  • 1 × 2.5ml spoonful of Pancrex V powder

24 × Pancrex V 125mg hard capsules contain:

  • Amylase 79,200 units
  • Lipase 70,800 units
  • Protease 3840 units

Equivalent products to 24 capsules

24 × Pancrex V 125mg hard capsules could be replaced with:

  • 15 × scoops of Creon Micro granules
  • 8 × Creon 10,000 unit capsules
  • 3 × Creon 25,000 unit capsules
  • 3 × Nutrizym 22 capsules
  • 9 × Pancrex V 340mg capsules
  • One and a half spoons of a 2.5ml spoonful of Pancrex V powder

32 × Pancrex V 125mg hard capsules contain:

  • Amylase 105,600 units
  • Lipase 94,400 units
  • Protease 5120 units

Equivalent products to 32 capsules

32 × Pancrex V 125mg hard capsules could be replaced with:

  • 20 × scoops of Creon Micro granules
  • 10 × Creon 10,000 unit capsules
  • 4 × Creon 25,000 unit capsules
  • 4 × Nutrizym 22 capsules
  • 12 × Pancrex V 340mg capsules
  • 2 × 2.5ml spoonful of Pancrex V powder

40 × Pancrex V 125mg hard capsules contain:

  • Amylase 132,000 units
  • Lipase 118,000 units
  • Protease 6400 units

Equivalent products to 40 capsules

40 × Pancrex V 125mg hard capsules could be replaced with:

  • 25 × scoops of Creon Micro granules
  • 13 × Creon 10,000 unit capsules
  • 5 × Creon 25,000 unit capsules
  • 5 × Nutrizym 22 capsules
  • 15 × Pancrex V 340mg capsules
  • Two and half spoons of a 2.5ml spoonful of Pancrex V powder

48 × Pancrex V 125mg hard capsules contain:

  • Amylase 158,400 units
  • Lipase 141,600 units
  • Protease 7680 units

Equivalent products to 48 capsules

48 × Pancrex V 125mg hard capsules could be replaced with:

  • 30 × scoops of Creon Micro granules
  • 15 × Creon 10,000 unit capsules
  • 6 × Creon 25,000 unit capsules
  • 6 × Nutrizym 22 capsules
  • 18 × Pancrex V 340mg capsules
  • 3 × 2.5ml spoonful of Pancrex V powder

Pancrex V 340mg hard capsules

Constituents

Each capsule contains:

  • Amylase 9000 units
  • Lipase 8000 units
  • Protease 430 units

3 × Pancrex V 340mg hard capsules contain:

  • Amylase 27,000 units
  • Lipase 24,000 units
  • Protease 1290 units

Equivalent products to 3 capsules

3 × Pancrex V 340mg hard capsules could be replaced with:

  • 5 × scoops of Creon Micro granules
  • 3 × Creon 10,000 unit capsules
  • 1 × Creon 25,000 unit capsule
  • 1 × Nutrizym 22 capsule
  • 8 × Pancrex V 125mg capsules
  • Half a spoon of a 2.5ml spoonful of Pancrex V powder

6 × Pancrex V 340mg hard capsules contain:

  • Amylase 54,000 units
  • Lipase 48,000 units
  • Protease 2580 units

Equivalent products to 6 capsules

6 × Pancrex V 340mg hard capsules could be replaced with:

  • 10 × scoops of Creon Micro granules
  • 5 × Creon 10,000 unit capsules
  • 2 × Creon 25,000 unit capsules
  • 2 × Nutrizym 22 capsules
  • 16 × Pancrex V 125mg capsules
  • 1 × 2.5ml spoonful of Pancrex V powder

9 × Pancrex V 340mg hard capsules contain:

  • Amylase 81,000 units
  • Lipase 72,000 units
  • Protease 3870 units

Equivalent products to 9 capsules

9 × Pancrex V 340mg hard capsules could be replaced with:

  • 15 × scoops of Creon Micro granules
  • 8 × Creon 10,000 unit capsules
  • 3 × Creon 25,000 unit capsules
  • 3 × Nutrizym 22 capsules
  • 24 × Pancrex V 125mg capsules
  • One and half spoons of a 2.5ml spoonful of Pancrex V powder

12 × Pancrex V 340mg hard capsules contain:

  • Amylase 108,000 units
  • Lipase 96,000 units
  • Protease 5160 units

Equivalent products to 12 capsules

12 × Pancrex V 340mg hard capsules could be replaced with:

  • 20 × scoops of Creon Micro granules
  • 10 × Creon 10,000 unit capsules
  • 4 × Creon 25,000 unit capsules
  • 4 × Nutrizym 22 capsules
  • 32 × Pancrex V 125mg capsules
  • 2 × 2.5ml spoonful of Pancrex V powder

15 × Pancrex V 340mg hard capsules contain:

  • Amylase 135,000 units
  • Lipase 120,000 units
  • Protease 6450 units

Equivalent products to 15 capsules

15 × Pancrex V 340mg hard capsules could be replaced with:

  • 25 × scoops of Creon Micro granules
  • 13 × Creon 10,000 unit capsules
  • 5 × Creon 25,000 unit capsules
  • 5 × Nutrizym 22 capsules
  • 40 × Pancrex V 125mg capsules
  • Two and half spoons of a 2.5ml spoonful of Pancrex V powder

18 × Pancrex V 340mg hard capsules contain:

  • Amylase 162,000 units
  • Lipase 144,000 units
  • Protease 7740 units

Equivalent products to 18 capsules

18 × Pancrex V 340mg hard capsules could be replaced with:

  • 30 × scoops of Creon Micro granules
  • 15 × Creon 10,000 unit capsules
  • 6 × Creon 25,000 unit capsules
  • 6 × Nutrizym 22 capsules
  • 48 × Pancrex V 125mg capsules
  • 3 × 2.5ml spoonful of Pancrex V powder

2 × Pancrex V 340mg hard capsules contain:

  • Amylase 18,000 units
  • Lipase 16,000 units
  • Protease 860 units

Equivalent products to 2 capsules

2 × Pancrex V 340mg hard capsules could be replaced with:

  • 2 × scoops of Creon Micro granules
  • 1 × Creon 10,000 unit capsules
  • Half a Creon 25,000 unit capsule
  • Quarter of a spoon of a 2.5ml spoonful of Pancrex V powder

3 × Pancrex V 340mg hard capsules contain:

  • Amylase 27,000 units
  • Lipase 24,000 units
  • Protease 1290 units

Equivalent products to 3 capsules

3 × Pancrex V 340mg hard capsules could be replaced with:

  • 4 × scoops of Creon Micro granules
  • 2 × Creon 10,000 unit capsules
  • 1 × Creon 25,000 unit capsule
  • Half of a spoon of a 2.5ml spoonful of Pancrex V powder

5 × Pancrex V 340mg hard capsules contain:

  • Amylase 45,000 units
  • Lipase 40,000 units
  • Protease 2150 units

Equivalent products to 5 capsules

5 × Pancrex V 340mg hard capsules could be replaced with:

  • 6 × scoops of Creon Micro granules
  • 3 × Creon 10,000 unit capsules
  • One and a half Creon 25,000 unit capsules
  • Three quarters of a spoon of a 2.5ml spoonful of Pancrex V powder

6 × Pancrex V 340mg hard capsules contain:

  • Amylase 54,000 units
  • Lipase 48,000 units
  • Protease 2580 units

Equivalent products to 6 capsules

6 × Pancrex V 340mg hard capsules could be replaced with:

  • 8 – 10 × scoops of Creon Micro granules
  • 4 – 5 × Creon 10,000 unit capsules
  • 2 × Creon 25,000 unit capsules
  • 1 × 2.5ml spoonful of Pancrex V powder

8 × Pancrex V 340mg hard capsules contain:

  • Amylase 72,000 units
  • Lipase 64,000 units
  • Protease 3440 units

Equivalent products to 8 capsules

8 × Pancrex V 340mg hard capsules could be replaced with:

  • 12 × scoops of Creon Micro granules
  • 6 × Creon 10,000 unit capsules
  • Two and a half Creon 25,000 unit capsules
  • One and a quarter spoons of a 2.5ml spoonful of Pancrex V powder

9 × Pancrex V 340mg hard capsules contain:

  • Amylase 81,000 units
  • Lipase 72,000 units
  • Protease 3870 units

Equivalent products to 9 capsules

9 × Pancrex V 340mg hard capsules could be replaced with:

  • 14 × scoops of Creon Micro granules
  • 7 × Creon 10,000 unit capsules
  • 3 × Creon 25,000 unit capsules
  • One and a half spoons of a 2.5ml spoonful of Pancrex V powder

11 × Pancrex V 340mg hard capsules contain:

  • Amylase 99,000 units
  • Lipase 88,000 units
  • Protease 4730 units

Equivalent products to 11 capsules

11 × Pancrex V 340mg hard capsules could be replaced with:

  • 16 × scoops of Creon Micro granules
  • 8 × Creon 10,000 unit capsules
  • Three and a half Creon 25,000 unit capsules
  • One and three quarter spoons of a 2.5ml spoonful of Pancrex V powder

12 × Pancrex V 340mg hard capsules contain:

  • Amylase 108,000 units
  • Lipase 96,000 units
  • Protease 5160 units

Equivalent products to 12 capsules

12 × Pancrex V 340mg hard capsules could be replaced with:

  • 18 – 20 × scoops of Creon Micro granules
  • 9 – 10 × Creon 10,000 unit capsules
  • 4 × Creon 25,000 unit capsules
  • 2 × 2.5ml spoonfuls of Pancrex V powder

Pancrex V powder

Constituents

Each 2.5mL spoonful is equivalent to 2g and contains:

  • Amylase 60,000 units
  • Lipase 50,000 units
  • Protease 2800 units

Half a 2.5mL spoonful of Pancrex V powder contains:

  • Amylase 30,000 units
  • Lipase 25,000 units
  • Protease 1400 units

Equivalent products to half a 2.5mL spoonful

Half a 2.5mL spoonful of Pancrex V powder could be replaced with:

  • 5 × scoops of Creon Micro granules
  • 3 × Creon 10,000 unit capsules
  • 1 × Creon 25,000 unit capsule
  • 1 × Nutrizym 22 capsule
  • 8 × Pancrex V 125mg hard capsules
  • 3 × Pancrex V 340mg hard capsules

1 × 2.5mL spoonful of Pancrex V powder contains:

  • Amylase 60,000 units
  • Lipase 50,000 units
  • Protease 2800 units

Equivalent products to 1 × 2.5mL spoonful

1 × 2.5mL spoonful of Pancrex V powder could be replaced with:

  • 10 × scoops of Creon Micro granules
  • 5 × Creon 10,000 unit capsules
  • 2 × Creon 25,000 unit capsules
  • 2 × Nutrizym 22 capsules
  • 16 × Pancrex V 125mg hard capsules
  • 6 × Pancrex V 340mg hard capsules

One and a half 2.5mL spoonfuls of Pancrex V powder contain:

  • Amylase 90,000 units
  • Lipase 75,000 units
  • Protease 4200 units

Equivalent products to one and a half a 2.5mL spoonfuls

One and a half 2.5mL spoonfuls of Pancrex V powder could be replaced with:

  • 15 × scoops of Creon Micro granules
  • 8 × Creon 10,000 unit capsules
  • 3 × Creon 25,000 unit capsules
  • 3 × Nutrizym 22 capsules
  • 24 × Pancrex V 125mg hard capsules
  • 9 × Pancrex V 340mg hard capsules

2 × 2.5mL spoonful of Pancrex V powder contains:

  • Amylase 120,000 units
  • Lipase 100,000 units
  • Protease 5600 units

Equivalent products to 2 × 2.5mL spoonful

2 × 2.5mL spoonful of Pancrex V powder could be replaced with:

  • 20 × scoops of Creon Micro granules
  • 10 × Creon 10,000 unit capsules
  • 4 × Creon 25,000 unit capsules
  • 4 × Nutrizym 22 capsules
  • 32 × Pancrex V 125mg hard capsules
  • 12 × Pancrex V 340mg hard capsules

Two and a half 2.5mL spoonfuls of Pancrex V powder contains:

  • Amylase 150,000 units
  • Lipase 125,000 units
  • Protease 7000 units

Equivalent products to two and a half 2.5mL spoonfuls

Two and a half a 2.5mL spoonfuls of Pancrex V powder could be replaced with:

  • 25 × scoops of Creon Micro granules
  • 13 × Creon 10,000 unit capsules
  • 5 × Creon 25,000 unit capsules
  • 5 × Nutrizym 22 capsules
  • 40 × Pancrex V 125mg hard capsules
  • 15 × Pancrex V 340mg hard capsules

3 × 2.5mL spoonful of Pancrex V powder contains:

  • Amylase 180,000 units
  • Lipase 150,000 units
  • Protease 8400 units

Equivalent products to 3 × 2.5mL spoonful

3 × 2.5mL spoonful of Pancrex V powder could be replaced with:

  • 30 × scoops of Creon Micro granules
  • 15 × Creon 10,000 unit capsules
  • 6 × Creon 25,000 unit capsules
  • 6 × Nutrizym 22 capsules
  • 48 × Pancrex V 125mg hard capsules
  • 18 × Pancrex V 340mg hard capsules

Quarter of a 2.5mL spoonful of Pancrex V powder contains:

  • Amylase 15,000 units
  • Lipase 12,500 units
  • Protease 700 units

Equivalent products to quarter of a 2.5mL spoonful

Quarter of a 2.5mL spoonful of Pancrex V powder could be replaced with:

  • 2 × scoops of Creon Micro granules
  • 1 × Creon 10,000 unit capsule
  • Half of a Creon 25,000 unit capsules
  • 2 × Pancrex V 340mg hard capsules

Half a 2.5mL spoonful of Pancrex V powder contains:

  • Amylase 30,000 units
  • Lipase 25,000 units
  • Protease 1400 units

Equivalent products to half a 2.5mL spoonful

Half a 2.5mL spoonful of Pancrex V powder could be replaced with:

  • 4 × scoops of Creon Micro granules
  • 2 × Creon 10,000 unit capsules
  • 1 × Creon 25,000 unit capsule
  • 3 × Pancrex V 340mg hard capsules

Three-quarters of a 2.5mL spoonful of Pancrex V powder contains:

  • Amylase 45,000 units
  • Lipase 37,500 units
  • Protease 2100 units

Equivalent products to three-quarters of a 2.5mL spoonful

Three-quarters of a 2.5mL spoonful of Pancrex V powder could be replaced with:

  • 6 × scoops of Creon Micro granules
  • 3 × Creon 10,000 unit capsules
  • One and a half Creon 25,000 unit capsules
  • 5 × Pancrex V 340mg hard capsules

1 × 2.5mL spoonful of Pancrex V powder contains:

  • Amylase 60,000 units
  • Lipase 50,000 units
  • Protease 2800 units

Equivalent products to 1 × 2.5mL spoonful

1 × 2.5mL spoonful of Pancrex V powder could be replaced with:

  • 8 – 10 × scoops of Creon Micro granules
  • 4 – 5 × Creon 10,000 unit capsules
  • 2 × Creon 25,000 unit capsules
  • 6 × Pancrex V 340mg hard capsules

One and a quarter 2.5mL spoonfuls of Pancrex V powder contain:

  • Amylase 75,000 units
  • Lipase 62,500 units
  • Protease 3500 units

Equivalent products to one and a quarter 2.5mL spoonfuls

One and a quarter 2.5mL spoonfuls of Pancrex V powder could be replaced with:

  • 12 × scoops of Creon Micro granules
  • 6 × Creon 10,000 unit capsules
  • Two and a half Creon 25,000 unit capsules
  • 8 × Pancrex V 340mg hard capsules

One and a half 2.5mL spoonfuls of Pancrex V powder contain:

  • Amylase 90,000 units
  • Lipase 75,000 units
  • Protease 4200 units

Equivalent products to one and a half 2.5mL spoonfuls

One and a half 2.5mL spoonfuls of Pancrex V powder could be replaced with:

  • 14 × scoops of Creon Micro granules
  • 7 × Creon 10,000 unit capsules
  • 3 × Creon 25,000 unit capsules
  • 9 × Pancrex V 340mg hard capsules

One and three-quarter 2.5mL spoonfuls of Pancrex V powder contain:

  • Amylase 105,000 units
  • Lipase 87,500 units
  • Protease 4900 units

Equivalent products to one and three-quarter 2.5mL spoonfuls

One and three-quarter 2.5mL spoonfuls of Pancrex V powder could be replaced with:

  • 16 × scoops of Creon Micro granules
  • 8 × Creon 10,000 unit capsules
  • Three and a half Creon 25,000 unit capsules
  • 11 × Pancrex V 340mg hard capsules

2 × 2.5mL spoonfuls of Pancrex V powder contain:

  • Amylase 120,000 units
  • Lipase 100,000 units
  • Protease 5600 units

Equivalent products to 2 × 2.5mL spoonfuls

2 × 2.5mL spoonfuls of Pancrex V powder could be replaced with:

  • 18 – 20 × scoops of Creon Micro granules
  • 9 – 10 × Creon 10,000 unit capsules
  • 4 × Creon 25,000 unit capsules
  • 12 × Pancrex V 340mg hard capsules

Where doses require half capules, this can be achieved by opening the capsule and halving the contents by eye.

The required amount can be given as per the instructions in the BNF, which state:

Manufacturer advises gastro-resistant granules should be mixed with slightly acidic soft food or liquid such as apple juice, and then swallowed immediately without chewing. Capsules containing enteric-coated granules can be opened and the granules administered in the same way. For infants, Creon® Micro granules can be mixed with a small amount of milk on a spoon and administered immediately—granules should not be added to the baby’s bottle.

Prescribing and ordering advice

Our main article summarises overall current advice on the prescribing and ordering of PERTs.

Prescribing and ordering available pancreatic enzyme replacement therapies

The availability of pancreatic enzyme replacement therapies (PERTs) varies currently. Use our resources and mini-tool to find matches for licensed products.

Update history

  1. Link to Position Statement from Pancreatic Society of Great Britain and Ireland updated to latest version. Includes information on unlicensed product, Pangrol.
  1. Link to NPPG website amended to include their position statement.
  1. Published

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