A range of DPP-4 inhibitor ('gliptin') formulations are suitable for use in adults with swallowing difficulties

Using our advice

Please see Medicines suitable for adults with swallowing difficulties

The choice of medicine formulation should be made on an individual basis, taking account of patient factors. Follow our stepwise guide Choosing medicines formulations in swallowing difficulties

Licensed medicines in suitable formulations

Sitagliptin 100mg/5ml oral solution

Available as a licensed product. It has a 60-day expiry once opened and does not require fridge storage.

Sitagliptin 25mg/ml oral solution

Available as a licensed product. it has a 90-day expiry once opened and must be stored in a fridge.

Licensed medicines used ‘off-label’

Alogliptin tablets

Film-coated but can be crushed and mixed with water or given with soft food. The crushed tablets may taste bitter.

Alogliptin with metformin tablets

Film-coated but can be crushed and mixed with water or given with soft food. The crushed tablets may taste bitter.

Linagliptin tablets

Film-coated but can be crushed and mixed with water or given with soft food.

Linagliptin with metformin tablets

Film-coated but can be crushed and mixed with water or given with soft food.

Linagliptin with empagaliflozin tablets

Film-coated but can be crushed and mixed with water or given with soft food.

Saxagliptin tablets

Film-coated but can be crushed and mixed with water or given with soft food.

Saxagliptin with metformin tablets

Film-coated but can be crushed and mixed with water or given with soft food.

Saxagliptin with dapagliflozin tablets

Film-coated but can be crushed and mixed with water or given with soft food.

Sitagliptin tablets

Film-coated but dissolve rapidly. Can be dispersed in water, or crushed and mixed with water or given with soft food. The crushed tablets may taste unpleasant.

Sitagliptin with metformin tablets

Film-coated but can be crushed and mixed with water or given with soft food. The crushed tablets may taste unpleasant.

Vildagliptin tablets

Can be crushed and mixed with water or given with soft food.

Vildagliptin with metformin tablets

Film-coated but can be crushed and mixed with water or given with soft food.

Special-order medicines

In view of the licensed products available, special-order preparations are unlikely to be required.

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