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Preparing Comirnaty 3 (THREE) (JN.1) concentrate vaccine

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Topics: COVID-19 vaccinePreparing

An example SOP for preparing Comirnaty 3 (THREE) (JN.1) concentrate vaccine

This article forms part of a series
  1. Managing COVID-19 Vaccines: Guidance and SOPs
    1. Ordering, receiving and storing COVID-19 vaccines
    2. Transporting COVID-19 vaccines
    3. Safe and secure handling, spillage and disposal of COVID-19 vaccines
    4. Moving COVID-19 vaccines legally within the NHS
    5. Preparing Comirnaty 30 micrograms (JN.1) vaccine
    6. Preparing Comirnaty 10 (JN.1) ready to use vaccine
    7. Preparing Comirnaty 3 (THREE) (JN.1) concentrate vaccine
    8. Preparing Spikevax (JN.1) vaccine

Understanding our terminology

Comirnaty (JN.1) 3 micrograms/modified) bretovameran must be prepared carefully following the manufacturer’s instructions. We refer to it as Comirnaty 3 (THREE) (JN.1) concentrate in our web articles. 

Example procedure

We have produced an example template Standard Operating Procedure (SOP) for the preparation of the Comirnaty 3 (THREE) (JN.1) concentrate vaccine.  

Please note, the dose volume has changed from previous Comirnaty 3 (THREE) vaccines and is now 0.3mL. 

The attachment is presented in Word to enable adaptation locally, or as reference source to check that existing local procedures are robust and comprehensive. Within the SOP, red text indicates where detail is to be added locally. 

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