The purpose of the study was to investigate the chemical and physical stability of Pemetrexed (as the
disodium salt) 2mg/mL and 13.5mg/mL in 100mL Sodium Chloride 0.9%w/v Intravenous Infusion bags.

The work performed for this stability study was carried out by Quality Control North West (QCNW) Liverpool.

This paper has been updated following the publication of the USP monograph. There is also a justification for the shelf life assigned.

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