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Interactions

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Understanding direct oral anticoagulant (DOAC) interactions

5 January 2024It is important to understand the risks, mechanisms of interactions and actions to take when prescribing medicines with DOACs.

Questions to ask when reviewing herbal medicines and interactions

28 March 2024Information should be gathered about the patient and herbal medicine to enable risk assessment and decision making on the interaction.

Herbal interactions: resources to support answering questions

28 March 2024Suggested resources to help healthcare professionals find information to answer questions about herbal interactions.

Managing interactions between macrolides and statins

24 November 2023The use of statins can be continued with azithromycin. However, the interaction risks need to be managed if clarithromycin or erythromycin are required.

Managing interactions with methotrexate

28 December 2023Guidance on frequently asked questions on medicine interactions with low dose methotrexate.

Considering drug interactions with smoking

31 October 2023Tobacco smoke can induce liver enzymes, affecting drug metabolism. Some medicines may need dose adjustment or monitoring if a person stops or starts smoking.

Drug interactions: resources to support answering questions

19 January 2023Suggested resources to help primary care healthcare professionals find information to answer questions about drug interactions

What is the clinical significance of potential drug interactions with local anaesthetic preparations used in primary care dentistry?

30 July 2020This updated Medicines Q&A explores the clinical significance of potential interactions between dental local anaesthetic preparations and other medicines as listed in the BNF and…

Understanding complementary medicines

28 March 2024Points to consider when advising on the use of complementary medicines.

Managing interactions with direct oral anticoagulants (DOACs)

5 January 2024Interactions with apixaban, dabigatran, edoxaban or rivaroxaban can result in increased risks of a bleed or thrombosis. We advise on management options.
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