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Considerations when choosing an alternative antidepressant

17 February 2023Consider the risks associated with switching an antidepressant for depression, the patient's individual circumstances and when to seek specialist advice.

Monitoring a person during and after antidepressant switching

17 February 2023Review people at appropriate time points; advise on what to expect and report; and beware of the possibility of withdrawal symptoms and serotonin syndrome.

Establishing if a person needs to switch their antidepressant

17 February 2023Prior response, side-effects, new contraindications, and current depression symptoms may require switching antidepressants. When it is, establish shared goals.

Planning and agreeing an antidepressant switching strategy

17 February 2023Guidance on planning and implementing the antidepressant switch after the need and choice of antidepressant have been decided.

Tricyclics to other antidepressants: switching in adults

17 February 2023Suggested methods for switching safely between tricyclics or to other antidepressants. Switches requiring additional specialist support are highlighted.

SSRIs to other antidepressants: switching in adults

17 February 2023Suggested methods for switching safely between SSRIs or to other antidepressants. Switches requiring additional specialist support are highlighted.

Using contraception with enzyme-inducing medicines

13 February 2023Enzyme-inducing medicines reduce the effectiveness of certain contraceptives. Guidance on using contraception with these medicines is given.

Using antidiabetic medicines during breastfeeding

2 February 2023Insulin or metformin are the preferred choices during breastfeeding. Recommendations apply to full term and healthy infants only.

Using tricyclic antidepressants during breastfeeding

31 January 2023Imipramine and nortriptyline are the tricyclic antidepressants of choice. Recommendations apply to full term and healthy infants only.

Assessment and storage of medicines for the self-administration

25 January 2023Suitable medicines must be stored safely and securely in accordance with organisational policy, while still supporting self-administration
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