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Benzylpenicillin for Group B Streptococcus for use in neonates
19 January 2023
·
SPS PGD template for the intrapartum administration of benzylpenicillin for prevention of early-onset Group B Streptococcus (GBS) infection in neonates.
Using codeine, dihydrocodeine or tramadol during breastfeeding
17 January 2023
·
Tramadol and dihydrocodeine can be used while breastfeeding for pain control. Codeine should not be used . Advice applies to full term, healthy infants.
Using SSRI antidepressants during breastfeeding
13 January 2023
·
Paroxetine and sertraline are the Selective Serotonin Reuptake Inhibitors (SSRIs) of choice. Recommendations apply to full term and healthy infants only.
Accessing resources for patients on high risk medicines
19 December 2022
·
A number of resources are available to support the safe use of high-risk medicines. Healthcare professionals should ensure they are available for their patients
Switching between imatinib preparations
15 December 2022
·
Support for decision making when considering switching imatinib preparations including a locally adaptable patient information leaflet.
Using solid oral dosage form antibiotics in children
7 December 2022
·
Crushing or dispersing whole solid dosage forms or opening capsules is an "off-label" use. This includes use for Group A streptococcal infections.
Assigning stability to Zerbaxa (ceftolozane/tazobactam) in elastomeric infusers
16 November 2022
·
Assessment of the degradation profile and toxicity data for Zerbaxa is available for its use in Outpatient Parenteral Antimicrobial Therapy (OPAT) services
Switching between neostigmine and pyridostigmine
25 October 2022
·
Switching between neostigmine and pyridostigmine in myasthenia gravis requires care and application of a stepped process
Reversing an adult opioid overdose with naloxone
18 October 2022
·
A patient safety alert highlighted the risks of giving inappropriate doses of naloxone. We guide on using appropriate intravenous doses in the medical setting.
Managing constipation in people taking clozapine
14 October 2022
·
Constipation in people taking clozapine can be fatal. Guidance on preventing and managing constipation in these individuals is described.
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