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Dosing

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Using St Mark’s electrolyte solution

31 January 2024St Mark’s solution is an oral rehydration solution, which maintains fluid balance in conditions like short bowel syndrome. We guide on preparation and use.

Using folic acid with methotrexate in rheumatoid arthritis

20 February 2023Folic acid is used to reduce methotrexate associated adverse effects in people with rheumatoid arthritis. This page guides appropriate dosing.

Reversing an adult opioid overdose with naloxone

18 October 2022A patient safety alert highlighted the risks of giving inappropriate doses of naloxone. We guide on using appropriate intravenous doses in the medical setting.

Choosing equivalent doses of oral benzodiazepines

25 January 2022Approximate equivalent doses of oral benzodiazepines to diazepam. Doses are not exact because of differences between the medicines.

Giving CosmoFer® (iron dextran) as a total dose infusion

14 December 2021Use a stepped process to safely and rapidly correct iron deficiency in adults over 14 years in hospital.

Using a Patient Group Direction to adjust doses of medicines

16 November 2021This article outlines why PGDs cannot be used to adjust the dosage of a medicine already in an individual's possession.

Dosing

All our advice relating to specific dosing recommendations.

What is the optimal prokinetic dose of erythromycin in adults?

22 October 2020This updated Medicines Q&A evaluates the available evidence for the use of erythromycin as a prokinetic agent in adults Summary The ideal prokinetic dose of…

Inclusion of dose ranges in a single Patient Group Direction

9 September 2020The below summarises the considerations required if a single PGD is to include a range of doses.

Supply of aseptically Prepared Doses of IMPs Across Legal Boundaries Version 2 October 2019

11 November 2019This document has been developed by the NHS Quality Assurance Committee and National Pharmacy Clinical Trials Advisory Group with input provided by the MHRA Clinical…
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