Regularly updated material to support the introduction of adalimumab, eculizumab, natalizumab, ranibizumab, tocilizumab and ustekinumab biosimilars.

Understand the area

Biosimilar medicines are a type of biological medicine that offer the NHS opportunities to deliver better value for certain conditions
An overview of NHS England and NHS SPS roles in implementing biosimilar and key generic medicines and what to expect in 2025/26.
This webinar provided information and guidance to support organisations switch to the best value ustekinumab biosimilar
Governance should consider processes for approval, procurement and supply, prescribing and administration, monitoring, and pharmacovigilance.

Adalimumab

Resources to support the choice of adalimumab biosimilar within organisations.

Choosing between available adalimumab products

Understand the adalimumab products that are available on contract to the NHS. Choose between them appropriately for organisations or individuals.

Eculizumab

Resources to support the choice of eculizumab biosimilar within organisations.

Preparing to use eculizumab biosimilar

Introducing biosimilar eculizumab needs planning. Work with the multidisciplinary team to ensure familiarity with the area and develop an implementation plan.

Good governance when implementing eculizumab biosimilar

Governance should consider processes for approval, procurement and supply, prescribing and administration, monitoring, and pharmacovigilance.

The licence and supporting evidence for eculizumab biosimilars

Two licensed eculizumab biosimilars are available: Bekemv and Epysqli. Learn about the licensed indications, supporting evidence and key differences.

Natalizumab

Resources to support the choice of natalizumab biosimilar within organisations.

Preparing to use natalizumab biosimilar

Natalizumab biosimilar needs planning. Ensure you are familiar with the area and then develop an implementation plan working with the multidisciplinary team.

Good governance when implementing natalizumab biosimilar

Governance should consider processes for approval, procurement and supply, prescribing and administration, monitoring and pharmacovigilance.

The licence and supporting evidence for natalizumab biosimilar

One licensed natalizumab biosimilar is available: Tyruko. Learn about the licensed indications and supporting evidence.

Ranibizumab for ocular use

Resources to specifically support the introduction of ranibizumab biosimilar for ocular use.

Preparing to use ranibizumab biosimilar

Ranibizumab biosimilar needs planning. Ensure you are familiar with the area and then develop an implementation plan working with the multidisciplinary team

Good governance when implementing ranibizumab biosimilar

Governance should consider processes for approval; procurement and supply; prescribing and administration; monitoring; and pharmacovigilance

The licence and supporting evidence for ranibizumab biosimilars

Four licensed ranibizumab biosimilars are available: Byooviz, Ongavia, Rimmyrah and Ximluci. Learn about the licensed indications and supporting evidence

Tocilizumab

Resources to support the choice of tocilizumab biosimilar within organisations.

Preparing to use tocilizumab biosimilar

Introducing biosimilar tocilizumab needs planning. Work with the multidisciplinary team to ensure familiarity with the area and develop an implementation plan.

Good governance when implementing tocilizumab biosimilar

Governance should consider processes for approval, procurement and supply, prescribing and administration, monitoring, and pharmacovigilance.

The licence and supporting evidence for tocilizumab biosimilar

One licensed tocilizumab biosimilar is available: Tyenne. Learn about the licensed indications, supporting evidence and key differences.

Ustekinumab

Preparing to use ustekinumab biosimilar

Introducing biosimilar ustekinumab needs planning. Work with the multidisciplinary team to ensure familiarity with the area and develop an implementation plan.

Good governance when implementing ustekinumab biosimilar

Governance should consider processes for approval, procurement and supply, prescribing and administration, monitoring, and pharmacovigilance.

The licence and supporting evidence for ustekinumab biosimilars

Ustekinumab biosimilars (Pyzchiva, Steqeyma, Uzpruvo, Wezenla) are licensed. Learn about indications, formulations, supporting evidence and differences.

Implementing ustekinumab biosimilar

This webinar provided information and guidance to support organisations switch to the best value ustekinumab biosimilar
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