Licensed for intrathecal use
Products licensed for intrathecal use are the first line option and should be used wherever suitable.
AbbVie Ltd (Chirocaine®)
Strength
2.5 mg/mL in 10mL ampoules
5 mg/mL in 10mL ampoules
7.5 mg in 10mL ampoules
Altan Pharma
Strength
2.5 mg/mL in 10mL ampoules
5 mg/mL in 10mL ampoules
7.5mg/mL in 10mL ampoules
Fresenius
Strength
2.5mg/mL in 10mL ampoule
5mg/mL in 10mL ampoule
7.5mg/mL in 10mL ampoule
Not licensed for intrathecal use, limited information available
Products with partial information that are not licensed for intrathecal administration can still sometimes be used. Refer to the advice in our article and complete a risk assessment to enable you to interpret the details below and choose an appropriate product.
AbbVie Ltd (Chirocaine®)
Strength
1.25 mg/mL in 100mL/200mL bags
Excipients
Sodium chloride, sodium hydroxide, hydrochloric acid, water for injection
Osmolarity
No information
pH
No information
Endotoxin content
No information
Altan Pharma
Strength
Excipients
Sodium chloride, sodium hydroxide, hydrochloric acid, water for injection
Osmolarity
270 – 330 mOsmol/kg
pH
4.0 – 6.5
Endotoxin content
No information
Strength
1.25 mg/mL in 100mL and 200mL bags
Excipients
Sodium chloride, sodium hydroxide, hydrochloric acid, water for injection
Osmolarity
270 – 330 mOsmol/kg
pH
4.0 – 6.5
Endotoxin content
≤ 2.5 EU/mL
Fresenius
Strength
0.625 mg/mL solution for infusion in 100mL and 200mL bags
Excipients
Sodium Chloride, sodium hydroxide (for pH adjustment), hydrochloric acid (for pH adjustment), water for injection
Osmolarity
271 – 332 mOsmol/L
pH
4.0 – 6.0
Endotoxin content
≤ 0.525 EU/mL
Strength
1.25 mg/mL in 100mL and 200mL bags
Excipients
Sodium Chloride, sodium hydroxide (for pH adjustment), hydrochloric acid (for pH adjustment), water for injection
Osmolarity
271 – 332 mOsmol/L
pH
4.0 – 6.0
Endotoxin content
≤ 1.05 EU/mL
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