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Gastrointestinal disorders

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Using loperamide in high output stoma or short bowel syndrome

7 November 2024This guidance explores the dosing and monitoring advice when using high dose loperamide to reduce high stoma output or in short bowel syndrome in adults.

Good governance when implementing ustekinumab biosimilar

2 August 2024Governance should consider processes for approval, procurement and supply, prescribing and administration, monitoring, and pharmacovigilance.

The licence and supporting evidence for ustekinumab biosimilars

2 August 2024Ustekinumab biosimilars (Pyzchiva, Steqeyma, Uzpruvo, Wezenla) are licensed. Learn about indications, formulations, supporting evidence and differences.

Preparing to use ustekinumab biosimilar

16 July 2024Introducing biosimilar ustekinumab needs planning. Work with the multidisciplinary team to ensure familiarity with the area and develop an implementation plan.

Using and prescribing thiamine in alcohol dependence

6 June 2024Intramuscular and intravenous thiamine can be used to prevent complications of alcohol dependence such as Wernicke’s encephalopathy.

Prescribing and using thiamine to prevent refeeding syndrome

2 May 2024Intravenous thiamine for prevention of refeeding syndrome should be reserved for those with intestinal failure where the oral or enteral route is unavailable.

Treating nausea during breastfeeding

26 March 2024Some anti-emetics can be used with caution during breastfeeding, depending on the clinical situation. Recommendations apply to full term, healthy infants.

Treating rectal and anal disorders during breastfeeding

19 March 2024Rectal and anal topical preparations for haemorrhoids and anal fissures are compatible with breastfeeding. Recommendations apply to full term, healthy infants.

Using gastrointestinal antispasmodics during breastfeeding

8 March 2024Hyoscine butylbromide, propantheline or peppermint oil are preferred choices during breastfeeding. Recommendations apply to full term and healthy infants.

Treating heartburn and dyspepsia during breastfeeding

5 March 2024Antacids, alginates, H2-receptor antagonists or proton pump inhibitors can be used during breastfeeding. Recommendations are for full term and healthy infants.
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