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Using clopidogrel with proton pump inhibitors (PPIs)

22 May 2023Avoid the combined use of clopidogrel with omeprazole or esomeprazole due to a significant interaction. Other PPIs are considered safe with clopidogrel.

Managing pharmaceutical waste

1 September 2023Guidance and principles for managing waste generated from the use of medicines.

Using intramuscular injections in people on oral anticoagulants

20 September 2023Advice on risks related to use of small volume (less than 3mL) intramuscular (IM) injections in people on oral anticoagulants (for example, DOACs, warfarin)

Handling and preparation of sotrovimab

14 December 2021An outline process and supporting materials to help Trusts deploy sotrovimab

Clotrimazole pessaries for candidiasis

5 October 2021SPS PGD template for the supply of clotrimazole pessaries for treatment of vulvo-vaginal candidiasis.

Managing specific interactions with smoking

31 October 2023When individuals taking certain medicines stop, start or re-start smoking, monitoring and dose changes may be needed.

Using laxatives during breastfeeding

24 October 2023Any laxative can be used during breastfeeding although prucalopride should be used with caution. Recommendations apply to full term and healthy infants.

Using SSRI antidepressants during breastfeeding

13 January 2023Paroxetine and sertraline are the Selective Serotonin Reuptake Inhibitors (SSRIs) of choice. Recommendations apply to full term and healthy infants only.

Medication Restrictions for Patients Having CAR-T Cell Therapy V5

12 July 2022CAR-T Therapy requires some medicines to be restricted, this guidance provides details and recommended wash-out periods for restricted medicines.

Clozapine use in adults with swallowing difficulties

31 May 2023Guidance on clozapine administration including crushing tablets, importance of not missing doses and practical considerations regarding switching formulations
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