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Managing interactions with methotrexate

28 December 2023Guidance on frequently asked questions on medicine interactions with low dose methotrexate.

Managing interactions with direct oral anticoagulants (DOACs)

5 January 2024Interactions with apixaban, dabigatran, edoxaban or rivaroxaban can result in increased risks of a bleed or thrombosis. We advise on management options.

Managing interactions between macrolides and statins

24 November 2023The use of statins can be continued with azithromycin. However, the interaction risks need to be managed if clarithromycin or erythromycin are required.

Managing defective medicines

19 June 2023An overview of what defective medicines are and how they should be reported by NHS personnel.

Managing constipation in people taking clozapine

14 October 2022Constipation in people taking clozapine can be fatal. Guidance on preventing and managing constipation in these individuals is described.

Managing complexities of medication use across care boundaries

26 June 2024Exploring the risks for patients on complex or specialist medicines moving across care boundaries with a focus on strategies to reduce harms

Managing Patient Group Directions following amendments or changes

8 September 2020There are requirements for all PGDs to be resigned or reauthorised after any amendment or change made during its valid to/from dates

Managing PGDs following organisational change

3 February 2022Advice on the management of PGDs when organisations merge, cease to exist or services are transferred to a new provider to ensure safe care and good governance

Managing Controlled Drugs (CD) waste

1 September 2023Legislation and regulation governing the waste management of controlled drugs (CDs).

Managing COVID-19 and breastfeeding

6 October 2023Continue breastfeeding during COVID-19 infection, even if dexamethasone, Paxlovid, sotrovimab or tocilzumab are required. COVID-19 vaccines can also be given.
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