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Guidance

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Switching

Our advice on switching between medicines covers switching between antidepressants as well as a range of other common medicines switches.

Switching between oral prednisolone and IV hydrocortisone

29 September 2023Switching between oral prednisolone and intravenous (IV) hydrocortisone requires care due to the risk of adrenal insufficiency or adrenal crisis.

Questions to ask when giving advice on medicines and breastfeeding

4 December 2020Information should be gathered on both the mother and the infant. Questions are provided to help determine clinical details

Using vaccines during breastfeeding

26 October 2023All vaccinations, including live vaccines, can be given during breastfeeding. The only exception is yellow fever vaccine which is not recommended.

Using metronidazole during breastfeeding

22 December 2023Metronidazole can be used during breastfeeding for most usual treatment courses. Recommendations apply to full term, healthy infants.

Choosing equivalent doses of oral benzodiazepines

25 January 2022Approximate equivalent doses of oral benzodiazepines to diazepam. Doses are not exact because of differences between the medicines.

Feasibility and setting up of clinical trials at participating sites

12 December 2022An overview of the Sponsor Pharmacy's responsibilities during setup of a clinical trial as part of participating site management

Pharmacy Manual Checklist for Clinical Trials for ATIMPs

2 March 2023Pharmacy Manual content expectations for optimal site implementation of ATIMP Clinical Trials.

Monitoring and auditing clinical trials by participating sites

12 December 2022An overview of the Sponsor Pharmacy's responsibilities for monitoring and auditing a clinical trial as part of participating site management

Closing clinical trials

12 December 2022Sponsor pharmacy responsibilities during trial closure and the final monitoring visit
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