Patient Group Directions

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Patient Group Directions

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Off-label or unlicensed product use under HMR 2012 exemptions

8 April 2026A legal position summary regarding the sale, supply or administration of off-label/unlicensed products under Schedule 17 of the Human Medicines Regulations 2012

Managing Patient Group Directions following amendments or changes

8 April 2026There are requirements for all Patient Group Directions (PGDs) to be resigned or reauthorised after any amendment or change made during its valid to/from dates

Repeat supply or administration of medicines under PGD

8 April 2026Patient Group Directions are not an appropriate mechanism for regular repeated supplies or administration of a medicine; repeat medicines should be prescribed.

PGD use in Hospital at Home services, including Virtual Wards

8 April 2026Considerations required before implementing Patient Group Direction (PGDs) in Hospital at Home, including virtual ward, services

Delegating PGD authorisation by a Local Authority

8 April 2026It is not permitted for a Local Authority to delegate the authorisation of Patient Group Directions using a Section 75 partnership agreement.

Off label medicine use under a Patient Group Direction

8 April 2026This article explains the legislation and guidance on the use of PGDs when a licensed medicine is to be used outside its licence ('off-label').

Seasonal influenza vaccination and occupational health services

1 April 2026Advice on medicines mechanisms for the administration of influenza vaccinations to healthcare staff.

Retaining legal mechanism documentation

1 April 2026Advice on the retention of all records relating to legal mechanisms, such as PSDs, PGDs, VGDs and Written Instructions

Using written instructions in occupational health services

1 April 2026Written instructions can be used as part of an occupational health service to supply/administer medicines to staff within the organisation.

Pharmacy technicians working under Patient Group Directions

5 June 2026Useful resources and further information for pharmacy technicians working under PGDs