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Benzylpenicillin for Group B Streptococcus for use in neonates

19 January 2023SPS PGD template for the intrapartum administration of benzylpenicillin for prevention of early-onset Group B Streptococcus (GBS) infection in neonates.

Flumazenil injection for reversal of midazolam

5 October 2021SPS PGD template for administering flumazenil for reversal of sedative effects of midazolam in conscious sedation by registered Paramedics and Nurses.

Diazepam rectal tubes for managing seizures

5 October 2021SPS PGD template for administering diazepam rectal tubes for the management of seizures by registered Paramedics and Nurses.

Using opioids for pain relief during pregnancy

10 August 2022Opioid analgesics may be used at any stage of pregnancy at the lowest effective dose for the short-term relief of pain when other analgesics are not effective.

Using clopidogrel with proton pump inhibitors (PPIs)

22 May 2023Avoid the combined use of clopidogrel with omeprazole or esomeprazole due to a significant interaction. Other PPIs are considered safe with clopidogrel.

Using intramuscular injections in people on oral anticoagulants

20 September 2023Advice on risks related to use of small volume (less than 3mL) intramuscular (IM) injections in people on oral anticoagulants (for example, DOACs, warfarin)

Handling and preparation of sotrovimab

14 December 2021An outline process and supporting materials to help Trusts deploy sotrovimab

Clotrimazole pessaries for candidiasis

5 October 2021SPS PGD template for the supply of clotrimazole pessaries for treatment of vulvo-vaginal candidiasis.

Managing specific interactions with smoking

31 October 2023When individuals taking certain medicines stop, start or re-start smoking, monitoring and dose changes may be needed.

Using laxatives during breastfeeding

24 October 2023Any laxative can be used during breastfeeding although prucalopride should be used with caution. Recommendations apply to full term and healthy infants.

SPS - Specialist Pharmacy Service

NHS