Adverse effects
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Commonly used medicines associated with QT interval prolongation
24 August 2026Examples of medicines known to prolong the QT interval. Medicines are grouped by therapeutic class and are not an exhaustive list.
Managing medicines associated with QT interval prolongation
24 August 2026Guidance on patient assessment and management of medicines associated with QT interval prolongation.
Managing peripheral oedema caused by calcium channel blockers
26 May 2026All calcium channel blockers (CCBs) can cause peripheral oedema. Incidence varies by choice and patient factors. Several management options are available.
Avoid prescribing desiccated (natural) thyroid extract
13 January 2026Levothyroxine is the recommended treatment for hypothyroidism. Desiccated or natural thyroid extracts (DTE) should not be prescribed in primary care.
Managing medicines for people with sulfonamide allergy
2 October 2024Points to consider when prescribing and supplying medicines to people with sulfonamide allergy.
Managing reactions to dental local anaesthetic injections
30 July 2024Reactions to dental local anaesthetics (LA) are usually psychogenic. We describe symptoms and management of allergy, adverse effects and psychogenic reactions.
Adverse drug reactions: resources to support answering questions
20 March 2023Suggested resources to help primary care healthcare professionals find information to answer questions about side-effects of medicines
Managing constipation in people taking clozapine
14 October 2022Constipation in people taking clozapine can be fatal. Guidance on preventing and managing constipation in these individuals is described.