Adverse effects
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Adverse drug reactions: resources to support clinical decisions
21 September 2026Suggested resources to help healthcare professionals find information about side-effects of medicines.
Managing medicines associated with QT interval prolongation
14 September 2026Guidance on patient assessment and management of medicines associated with QT interval prolongation.
Choosing medicines in sulfonamide hypersensitivity
9 September 2026People allergic to one sulfonamide antibiotic should avoid other sulfonamide antibiotics. We advise on prescribing non-antibiotic sulfonamides in this situation
Commonly used medicines associated with QT interval prolongation
27 August 2026Examples of medicines known to prolong the QT interval. Medicines are grouped by therapeutic class and are not an exhaustive list.
Managing peripheral oedema caused by calcium channel blockers
26 May 2026All calcium channel blockers (CCBs) can cause peripheral oedema. Incidence varies by choice and patient factors. Several management options are available.
Avoid prescribing desiccated (natural) thyroid extract
13 January 2026Levothyroxine is the recommended treatment for hypothyroidism. Desiccated or natural thyroid extracts (DTE) should not be prescribed in primary care.
Managing reactions to dental local anaesthetic injections
30 July 2024Reactions to dental local anaesthetics (LA) are usually psychogenic. We describe symptoms and management of allergy, adverse effects and psychogenic reactions.
Managing constipation in people taking clozapine
14 October 2022Constipation in people taking clozapine can be fatal. Guidance on preventing and managing constipation in these individuals is described.