Scope of templates
The SPS national Patient Group Direction (PGD), protocol and written-instruction templates are written in alignment with relevant national guidance to be applicable to a wide range of services, clinical environments and patient cohorts.
The templates are intended to support, not substitute, relevant national guidance and as such should always be used in practice alongside supporting guidance.
As the templates are intended to be used in a variety of different services and clinical environments, organisations may need to locally adapt the content to meet the needs of their local populations or service model, and other aspects such as laboratory reporting systems. For more information see Implementing the SPS legal mechanism templates (SPS page).
Transfer of templates to an accessible format
- All SPS PGD and protocol templates are being transferred to an accessible format as part of wider work within SPS to improve accessibility and user experience.
- All new and updated templates published from autumn 2025 will be in the accessible format.
- Current published templates will be gradually transferred to the new format and republished. As there will be no change to the clinical or pharmaceutical content the version number and expiry dates will remain unchanged. This work will be completed by autumn 2026.
- There is no requirement for organisations using previous non-accessible formats of the templates to transfer to the new accessible templates upon publication unless they wish to do so.
New or recently updated templates
Our most recently updated or new templates, listed in date order.
October 2026
- Aciclovir for shingles
- Valaciclovir for shingles
- Penicillin V (phenoxymethylpenicillin) for sore throat
- Clarithromycin for sore throat
- Erythromycin for sore throat
- Otigo (phenazone with lidocaine) ear drops for otitis media
- Amoxicillin for otitis media
- Clarithromycin for otitis media
- Erythromycin for otitis media
- Fluticasone furoate nasal spray for sinusitis
- Mometasone furoate monohydrate nasal spray for sinusitis
- Penicillin V (phenoxymethylpenicillin) for sinusitis
- Clarithromycin for sinusitis
- Doxycycline for sinusitis
- Erythromycin for sinusitis
- Flucloxacillin for infected insect bites or stings
- Clarithromycin for infected insect bites or stings
- Erythromycin for infected insect bites or stings
- Hydrogen peroxide 1% cream for impetigo
- Fusidic acid 2% cream for impetigo
- Flucloxacillin for impetigo
- Clarithromycin for impetigo
- Erythromycin for impetigo
July 2026
- Intrapartum administration of benzylpenicillin sodium
- Clotrimazole cream for candidiasis and candidal balanoposthitis
- Clotrimazole pessaries for candidiasis
- Fluconazole 150mg capsule for candidiasis
- Progestogen only pill (POP) for contraception
- Progestogen-Only Intra-Uterine Device (LNG-IUD) for contraception
- Medroxyprogesterone acetate (DMPA) IM injection for contraception
- Medroxyprogesterone acetate (DMPA) SC injection for contraception
- Combined hormonal contraceptive transdermal patch
- Combined hormonal contraceptive vaginal ring
- Combined oral hormonal contraceptive (COC) in reproductive health
- Etonogestrel (e.g. Nexplanon®) implant for contraception
Ambulance
Created by SPS with the support of National Ambulance Service Medical Directors (NASMeD) and Joint Royal Colleges Ambulance Liaison Committee (JRCALC).
- Diazepam injection for seizures or symptomatic cocaine toxicity
- Rectal diazepam for managing seizures
- Buccal midazolam for seizures or symptomatic cocaine toxicity
- Flumazenil injection for reversal of midazolam
Community Pharmacy
The NHS Pharmacy First Service PGDs/protocols can be found at:
Community Pharmacy advanced service specification: NHS Pharmacy First Service
Any queries regarding the NHS Pharmacy First Service PGDs/protocols should be directed to: ENGLAND.CommunityPharmacy@nhs.net
Infection and infectious diseases
Created by SPS with the support of specialist stakeholders including National Institute for Health and Care Excellence (NICE), Royal College of General Practitioners (RCGP), British Association for Sexual Health and HIV (BASHH), UK Health Security Agency (UKHSA) and NHS England (NHSE).
Central nervous system infections
Hepatitis C
Created by SPS with the support of specialist stakeholders working within clinical practice.
The hepatitis C PGDs have now been shared with the Operational Delivery Networks (ODNs) by the hepatitis C elimination team at NHS England.
Any queries regarding access to the hepatitis C PGDs should be directed to: ENGLAND.hepc-enquiries@nhs.net
Respiratory tract infections
- Doxycycline for sinusitis
- Otigo (phenazone with lidocaine) ear drops for otitis media
- Fluticasone furoate nasal spray for sinusitis
- Amoxicillin for otitis media
- Clarithromycin for sore throat
- Penicillin V (phenoxymethylpenicillin) for sinusitis
- Mometasone furoate monohydrate nasal spray for sinusitis
- Clarithromycin for otitis media
- Penicillin V (phenoxymethylpenicillin) for sore throat
- Clarithromycin for sinusitis
- Erythromycin for sinusitis
- Erythromycin for otitis media
- Erythromycin for sore throat
Skin infections
- Valaciclovir for shingles
- Flucloxacillin for infected insect bites or stings
- Hydrogen peroxide 1% cream for impetigo
- Clarithromycin for impetigo
- Clarithromycin for infected insect bites or stings
- Flucloxacillin for impetigo
- Erythromycin for infected insect bites or stings
- Fusidic acid 2% cream for impetigo
- Erythromycin for impetigo
- Aciclovir for shingles
- Doxycycline and metronidazole for human and animal bites
- Co-amoxiclav for human and animal bites
Skin infestations
Urinary tract infections
Occupational health services
Written instruction templates for use in occupational health services, created by SPS and published annually.
Pregnancy and supportive medicines
For use in antenatal and maternity services across all healthcare sectors.
Created by SPS and NHSE, with the support of specialist stakeholders working within clinical practice and the Royal College of Obstetrics and Gynaecology (RCOG), as part of the wider Preventative Medicines in Pregnancy programme.
- Intrapartum administration of benzylpenicillin sodium
- Omeprazole for use within antenatal and maternity services
- Terbutaline injection for use in labour within maternity services
- Aspirin tablets for use within antenatal and maternity services
- Folic acid 5mg tablets for use during pregnancy
Public Health
PGD templates are developed by UKHSA for a variety of clinical scenarios.
Note these PGDs are not developed by SPS; any queries regarding these templates should be directed to the UKHSA immunisation team at immunisation@ukhsa.gov.uk
Radiology
Created by SPS, NHS England, the Royal College of Radiologists (RCR) and the Society and College of Radiographers (SCoR), with the support of specialists working within NHS clinical practice. For use in radiology service in NHS England commissioned services.
- Sodium chloride 0.9% in multi injector devices
- Ioversol contrast agent
- Iomeprol contrast agent
- Iopamidol contrast agent
- Iohexol contrast agent
- Iodixanol contrast agent
- Intravenous hyoscine butylbromide
- Gadoxetate disodium contrast agent
- Gadoteridol contrast agent
- Gadobenate dimeglumine contrast agent
- Gadobutrol contrast agent
- Gadoteric acid contrast agent
- Gadopiclenol contrast agent
Reproductive health and contraception
For use within reproductive health and contraception services across all healthcare sectors.
Created by SPS and the College of Sexual and Reproductive Health (CoSRH), with the support of specialist stakeholders working within clinical practice.
- Copper Intrauterine Device (Cu-IUD)
- Etonogestrel (e.g. Nexplanon®) implant for contraception
- Lidocaine injection for subdermal etonogestrel in contraception
- Progestogen-Only Intra-Uterine Device (LNG-IUD) for contraception
- Medroxyprogesterone acetate (DMPA) SC injection for contraception
- Combined hormonal contraceptive transdermal patch
- Combined hormonal contraceptive vaginal ring
- Progestogen only pill (POP) for contraception
- Medroxyprogesterone acetate (DMPA) IM injection for contraception
- Combined oral hormonal contraceptive (COC) in reproductive health
- Ulipristal acetate 30mg tablets for emergency contraception
- Levonorgestrel 1500 microgram tablets for emergency contraception
- Lidocaine plus prilocaine cream for IUD insertion or removal
- Lidocaine 10mg/ml spray for IUD insertion or removal
Sexual health
For use within sexual health services across all healthcare sectors.
Created by SPS and the British Association of Sexual Health and HIV (BASHH)/British Association of HIV (BHIVA), with the support of specialist stakeholders working within clinical practice.
- Fluconazole 150mg capsule for candidiasis
- Clotrimazole cream for candidiasis and candidal balanoposthitis
- Clotrimazole pessaries for candidiasis
- Ceftriaxone intramuscular injection for Neisseria gonorrhoeae
- Metronidazole (oral) for use within sexual health services
- Emtricitabine and tenofovir disoproxil (TD) tablets as PrEP
- Doxycycline for use within sexual health services
- Azithromycin (oral) for use within sexual health services
- Doxycycline post exposure prophylaxis (doxyPEP)
- Emtricitabine/tenofovir and raltegravir tablets for HIV PEP
- Podophyllotoxin (topical) for external anogenital warts
- Imiquimod 5% w/w cream for anogenital warts
- Emtricitabine and tenofovir alafenamide (TAF) tablets as PrEP
- Aciclovir (oral) for genital HSV infection
Smoking cessation
Created by SPS with the support of specialist stakeholders including the National Centre for Smoking Cessation and Training (NCSCT), College of Mental Health Pharmacy (CMHP) and NHSE.
Templates in development
No new templates currently in development.